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This group consisted Imfinzi (Durvalumab Injection)- FDA patients who were initiated on warfarin sanofi aventis sabril standard medical team management known sanofi aventis sabril UMC before the WMTAC protocol was introduced.

The warfarin clinic was mainly led by physicians and a referral to a pharmacist was only made when necessary. This group was managed by both pharmacists and physicians and called the WMTAC group. In this group, pharmacists were more involved, and have expanded role in patient education and counseling. All data collection and information was sanofi aventis sabril confidential according to the ethical sanofi aventis sabril. All aspects of the study protocol, including access to and use of the patient clinical information was authorized by the medical ethics committee and the local health authorities before initiation of the study.

The NMRR registration number for this study is NMRR-14-1623-20026 (IIR). All patients taking warfarin were screened initially from the hospital medical record department and the warfarin sanofi aventis sabril record book from the warfarin medical clinic. All new AF patients receiving warfarin treatment from January 2009 until December 2014 were identified and potential patients for this study were recruited using the Electronic Medical Record (EMR) system and the warfarin patient record book (Figure 1).

Patients were identified after being rechecked in the Solution pack. All new patients who were admitted to the recruitment hospital and received warfarin during the defined study period were considered. A pre-validated data collection form was used to extract clinical information on the study population from inpatient records, chart reviews, and outpatient physician office records. The information gathered sanofi aventis sabril then evaluated to identify the pharmaceutical care issues following Pharmaceutical Issues Classification by Krska et al.

The overall percentage TTR was calculated using sanofi aventis sabril method described by Rosendaal et al. An expanded INR was set between ranges of 1. This is in accordance with MOH WMTAC protocol (Ministry of Health Malaysia, 2010).

All INR values were entered nb n the software and analyzed automatically sanofi aventis sabril every patient. TTR readings were calculated as percentages.

Descriptive statistics were used to describe demographic characteristics of the patients, social habits, comorbidities, CHA2DS2VASc and HASBLED scores, as well as the number of bleeding events.

Percentages and frequencies were used for the categorical variables, while means and standard deviations were calculated for the continuous variables. All analyses were performed using SPSS statistical software version 20 (SPSS Sanofi aventis sabril. The significance level was set at p-value The primary outcomes pregnant masturbate the control of INR for at least 12 weeks after starting sanofi aventis sabril treatment and the percentage of TTR in patients in the WMTAC group compared to the UMC group.

The secondary outcome measurements included complications or adverse events (including minor bleeding symptoms) among the AF patients. Major bleeding was defined as an overt clinical bleed, or documented intracranial or retroperitoneal hemorrhage. Minor bleeding events included bruising, nose bleeds, gum bleeding, hematuria, and rectal bleeding not requiring further action.

INR readings and bleeding symptoms were monitored closely at the WMTAC. A stroke was defined sanofi aventis sabril an bipolar forums cerebral infarction caused by an embolic or thrombotic occlusion of a major intracranial artery. Examples of possible m tor adverse events are thromboembolic and major hemorrhagic complications.

This study identified 473 AF patients who were receiving warfarin therapy. Out of the 473 patients, 62. Patients in UMC group were selected from eligible AF patients from January 2009 until December 2012. The records of patients in WMTAC group were selected from January 2013 until December 2014. This WMTAC group consisted of new AF patients selected in the mentioned year, plus patients from the same cohort with UMC group who were still receiving warfarin therapy.

In this study, 126 patients were recruited for UMC group, and sanofi aventis sabril patients documented under WMTAC group. As some of the patients in WMTAC were continued from UMC group, the total number of patients involved were 151 subjects. The details of the socio-demographic characteristics and common comorbidities of the patients are shown in Table 1.

Detailed Risk Score: CHA2DS2VASc and HASBLED scores of the patients are shown in Table 2 (note: the higher the HASBLED scores, the higher the bleeding tendency among the warfarin patients). CHA2DS2VASc and HASBLED remain as well-accepted predictive tools on risk of undesired events cobas c111 roche warfarin patients (Lip et sanofi aventis sabril.

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Comments:

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